Show simple item record

dc.contributor.authorCooper, Dianeen_US
dc.contributor.authorHoffman, Margareten_US
dc.contributor.authorCarrara, Henrien_US
dc.contributor.authorRosenberg, Lynnen_US
dc.contributor.authorKelly, Judyen_US
dc.contributor.authorStander, Ilseen_US
dc.contributor.authorDenny, Lynnetteen_US
dc.contributor.authorWilliamson, Anna-Liseen_US
dc.contributor.authorShapiro, Samuelen_US
dc.date.accessioned2012-01-12T17:42:25Z
dc.date.available2012-01-12T17:42:25Z
dc.date.copyright2007en_US
dc.date.issued2007-11-27en_US
dc.identifier.citationCooper, Diane, Margaret Hoffman, Henri Carrara, Lynn Rosenberg, Judy Kelly, Ilse Stander, Lynnette Denny, Anna-Lise Williamson, Samuel Shapiro. "Determinants of sexual activity and its relation to cervical cancer risk among South African Women" BMC Public Health 7:341. (2007)en_US
dc.identifier.issn1471-2458en_US
dc.identifier.urihttp://hdl.handle.net/2144/3427
dc.description.abstractBACKGROUND. Invasive cervical cancer is the commonest cause of cancer morbidity and mortality in South African women. This study provides information on adult women's sexual activity and cervical cancer risk in South Africa. METHODS. The data were derived from a case-control study of hormonal contraceptives and cervical cancer risk. Information on age of sexual debut and number of lifetime sexual partners was collected from 524 incident cases and 1541 hospital controls. Prevalence ratios and adjusted prevalence ratios were utilised to estimate risk in exposures considered common. Crude and adjusted relative risks were estimated where the outcome was uncommon, using multiple logistic regression analysis. RESULTS. The median age of sexual debut and number of sexual partners was 17 years and 2 respectively. Early sexual debut was associated with lower education, increased number of life time partners and alcohol use. Having a greater number of sexual partners was associated with younger sexual debut, being black, single, higher educational levels and alcohol use. The adjusted odds ratio for sexual debut < 16 years and ≥ 4 life-time sexual partners and cervical cancer risk were 1.6 (95% CI 1.2 – 2.2) and 1.7 (95% CI 1.2 – 2.2), respectively. CONCLUSION. Lower socio-economic status, alcohol intake, and being single or black, appear to be determinants of increased sexual activity in South African women. Education had an ambiguous effect. As expected, cervical cancer risk is associated with increased sexual activity. Initiatives to encourage later commencement of sex, and limiting the number of sexual partners would have a favourable impact on risk of cancer of the cervix and other sexually transmitted infections.en_US
dc.description.sponsorshipNational Cancer Institute (R01 CA 73985)en_US
dc.language.isoenen_US
dc.publisherBioMed Centralen_US
dc.rightsCopyright 2007 Cooper et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.en_US
dc.rights.urihttp://creativecommons.org/licenses/by/2.0en_US
dc.titleDeterminants of Sexual Activity and Its Relation to Cervical Cancer Risk among South African Womenen_US
dc.typearticleen_US
dc.identifier.doi10.1186/1471-2458-7-341en_US
dc.identifier.pubmedid18042284en_US
dc.identifier.pmcid2228293en_US


Files in this item

This item appears in the following Collection(s)

Show simple item record

Copyright 2007 Cooper et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Except where otherwise noted, this item's license is described as Copyright 2007 Cooper et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.