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dc.contributor.authorCrookston, Benjamin T.en_US
dc.contributor.authorAlder, Stephen C.en_US
dc.contributor.authorBoakye, Isaacen_US
dc.contributor.authorMerrill, Ray M.en_US
dc.contributor.authorAmuasi, John H.en_US
dc.contributor.authorPorucznik, Christina A.en_US
dc.contributor.authorStanford, Joseph B.en_US
dc.contributor.authorDickerson, Ty T.en_US
dc.contributor.authorDearden, Kirk A.en_US
dc.contributor.authorHale, DeVon C.en_US
dc.contributor.authorSylverken, Justiceen_US
dc.contributor.authorSnow, Bryce S.en_US
dc.contributor.authorOsei-Akoto, Alexen_US
dc.contributor.authorAnsong, Danielen_US
dc.date.accessioned2012-01-11T21:43:53Z
dc.date.available2012-01-11T21:43:53Z
dc.date.copyright2010
dc.date.issued2010-2-2
dc.identifier.citationCrookston, Benjamin T, Stephen C Alder, Isaac Boakye, Ray M Merrill, John H Amuasi, Christina A Porucznik, Joseph B Stanford, Ty T Dickerson, Kirk A Dearden, DeVon C Hale, Justice Sylverken, Bryce S Snow, Alex Osei-Akoto, Daniel Ansong. "Exploring the relationship between chronic undernutrition and asymptomatic malaria in Ghanaian children" Malaria Journal 9:39. (2010)
dc.identifier.issn1475-2875
dc.identifier.urihttp://hdl.handle.net/2144/3241
dc.description.abstractBACKGROUND A moderate association has been found between asymptomatic parasitaemia and undernutrition. However, additional investigation using the gold standard for asymptomatic parasitaemia confirmation, polymerase chain reaction (PCR), is needed to validate this association. Anthropometric measurements and blood samples from children less than five years of age in a rural Ghanaian community were used to determine if an association exists between chronic undernutrition and PCR-confirmed cases of asymptomatic malaria. METHODS This was a descriptive cross-sectional study of 214 children less than five years of age from a community near Kumasi, Ghana. Blood samples and anthropometric measurements from these children were collected during physical examinations conducted in January 2007 by partners of the Barekuma Collaborative Community Development Programme. RESULTS Findings from the logistic model predicting the odds of asymptomatic malaria indicate that children who experienced mild, moderate or severe stunting were not more likely to have asymptomatic malaria than children who were not stunted. Children experiencing anaemia had an increased likelihood (OR = 4.15; 95% CI: 1.92, 8.98) of asymptomatic malaria. Similarly, increased spleen size, which was measured by ultrasound, was also associated with asymptomatic malaria (OR = 2.17; 95% CI: 1.44, 3.28). Fast breathing, sex of the child, and age of the child were not significantly associated with the asymptomatic malaria. CONCLUSIONS No significant association between chronic undernutrition and presence of asymptomatic malaria was found. Children who experience anaemia and children who have splenomegaly are more likely to present asymptomatic malaria. Programmes aimed at addressing malaria should continue to include nutritional components, especially components that address anaemia.en_US
dc.description.sponsorshipUniversity of Utahen_US
dc.language.isoenen_US
dc.publisherBioMed Centralen_US
dc.rightsCopyright 2010 Crookston et al; licensee BioMed Central Ltd.en_US
dc.rights.urihttp://creativecommons.org/licenses/by/2.0
dc.titleExploring the Relationship between Chronic Undernutrition and Asymptomatic Malaria in Ghanaian Childrenen_US
dc.typearticleen_US
dc.identifier.doi10.1186/1475-2875-9-39
dc.identifier.pubmedid20122258
dc.identifier.pmcid2837055


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Copyright 2010 Crookston et al; licensee BioMed Central Ltd.
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