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dc.contributor.authorHasselmo, Michael E.en_US
dc.contributor.authorBrandon, Mark P.en_US
dc.date.accessioned2012-01-11T17:18:52Z
dc.date.available2012-01-11T17:18:52Z
dc.date.copyright2008en_US
dc.date.issued2008-7-21en_US
dc.identifier.citationHasselmo, Michael E., Mark P. Brandon. "Linking Cellular Mechanisms to Behavior: Entorhinal Persistent Spiking and Membrane Potential Oscillations May Underlie Path Integration, Grid Cell Firing, and Episodic Memory" Neural Plasticity 2008:658323.en_US
dc.identifier.issn1687-5443en_US
dc.identifier.urihttp://hdl.handle.net/2144/3158
dc.description.abstractThe entorhinal cortex plays an important role in spatial memory and episodic memory functions. These functions may result from cellular mechanisms for integration of the afferent input to entorhinal cortex. This article reviews physiological data on persistent spiking and membrane potential oscillations in entorhinal cortex then presents models showing how both these cellular mechanisms could contribute to properties observed during unit recording, including grid cell firing, and how they could underlie behavioural functions including path integration. The interaction of oscillations and persistent firing could contribute to encoding and retrieval of trajectories through space and time as a mechanism relevant to episodic memory.en_US
dc.description.sponsorshipSilvio O. Conte Center (NIMH MH71702, MH60450); National Institute of Mental Health Research (MH60013, MH61492); National Science Foundation (SLC SBE 0354378); National Institute of Drug Abuse (DA16454).en_US
dc.language.isoenen_US
dc.publisherHindawi Publishing Corporationen_US
dc.rightsCopyright 2008 M. E. Hasselmo and M. P. Brandon. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.en_US
dc.titleLinking Cellular Mechanisms to Behavior: Entorhinal Persistent Spiking and Membrane Potential Oscillations May Underlie Path Integration, Grid Cell Firing, and Episodic Memoryen_US
dc.typearticleen_US
dc.identifier.doi10.1155/2008/658323en_US
dc.identifier.pubmedid18670635en_US
dc.identifier.pmcid2480478en_US


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