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dc.contributor.authorFaith, Jeremiah J.en_US
dc.contributor.authorDriscoll, Michael E.en_US
dc.contributor.authorFusaro, Vincent A.en_US
dc.contributor.authorCosgrove, Elissa J.en_US
dc.contributor.authorHayete, Borisen_US
dc.contributor.authorJuhn, Frank S.en_US
dc.contributor.authorSchneider, Stephen J.en_US
dc.contributor.authorGardner, Timothy S.en_US
dc.date.accessioned2012-01-11T00:40:02Z
dc.date.available2012-01-11T00:40:02Z
dc.date.issued2008-1en_US
dc.identifier.citationFaith, Jeremiah J., Michael E. Driscoll, Vincent A. Fusaro, Elissa J. Cosgrove, Boris Hayete, Frank S. Juhn, Stephen J. Schneider, Timothy S. Gardner. "Many Microbe Microarrays Database: uniformly normalized Affymetrix compendia with structured experimental metadata" Nucleic Acids Research 36(Database issue): D866-D870. (2008)en_US
dc.identifier.issn1362-4962en_US
dc.identifier.urihttp://hdl.handle.net/2144/3029
dc.description.abstractMany Microbe Microarrays Database (M3D) is designed to facilitate the analysis and visualization of expression data in compendia compiled from multiple laboratories. M3D contains over a thousand Affymetrix microarrays for Escherichia coli, Saccharomyces cerevisiae and Shewanella oneidensis. The expression data is uniformly normalized to make the data generated by different laboratories and researchers more comparable. To facilitate computational analyses, M3D provides raw data (CEL file) and normalized data downloads of each compendium. In addition, web-based construction, visualization and download of custom datasets are provided to facilitate efficient interrogation of the compendium for more focused analyses. The experimental condition metadata in M3D is human curated with each chemical and growth attribute stored as a structured and computable set of experimental features with consistent naming conventions and units. All versions of the normalized compendia constructed for each species are maintained and accessible in perpetuity to facilitate the future interpretation and comparison of results published on M3D data. M3D is accessible at http://m3d.bu.edu/.en_US
dc.description.sponsorshipOffice of Science (BER); U.S. Department of Energy (DEFG02-04ER63803, DE-FG02-07ER64388); The National Institute of General Medical Science (R01 GM078987); Joint National Science Foundation/National Institute of General Medical Sciences Mathematical Biology Programen_US
dc.language.isoenen_US
dc.publisherOxford University Pressen_US
dc.titleMany Microbe Microarrays Database: Uniformly Normalized Affymetrix Compendia with Structured Experimental Metadataen_US
dc.typearticleen_US
dc.identifier.doi10.1093/nar/gkm815en_US
dc.identifier.pubmedid17932051en_US
dc.identifier.pmcid2238822en_US


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