Period Concatenation Underlies Interactions Between Gamma and Beta Rhythms in Neocortex


Show simple item record Roopun, Anita K. en_US Kramer, Mark A. en_US Carracedo, Lucy M. en_US Kaiser, Marcus en_US Davies, Ceri H. en_US Traub, Roger D. en_US Kopell, Nancy J. en_US Whittington, Miles A. en_US 2012-01-09T14:57:56Z 2012-01-09T14:57:56Z 2008 en_US 2008-04-08 en_US
dc.identifier.citation Roopun, Anita K., Mark A. Kramer, Lucy M. Carracedo, Marcus Kaiser, Ceri H. Davies, Roger D. Traub, Nancy J. Kopell, Miles A. Whittington. "Period Concatenation Underlies Interactions Between Gamma and Beta Rhythms in Neocortex" Frontiers in Cellular Neuroscience 2 (2008) en_US
dc.identifier.issn 1662-5102 en_US
dc.description.abstract The neocortex generates rhythmic electrical activity over a frequency range covering many decades. Specific cognitive and motor states are associated with oscillations in discrete frequency bands within this range, but it is not known whether interactions and transitions between distinct frequencies are of functional importance. When coexpressed rhythms have frequencies that differ by a factor of two or more interactions can be seen in terms of phase synchronization. Larger frequency differences can result in interactions in the form of nesting of faster frequencies within slower ones by a process of amplitude modulation. It is not known how coexpressed rhythms, whose frequencies differ by less than a factor of two may interact. Here we show that two frequencies (gamma - 40Hz and beta2 - 25Hz), coexpressed in superficial and deep cortical laminae with low temporal interaction, can combine to generate a third frequency (beta1 - 15Hz) showing strong temporal interaction. The process occurs via period concatenation, with basic rhythm-generating microcircuits underlying gamma and beta2 rhythms forming the building blocks of the beta1 rhythm by a process of addition. The mean ratio of adjacent frequency components was a constant - approximately the golden mean - which served to both minimize temporal interactions, and permit multiple transitions, between frequencies. The resulting temporal landscape may provide a framework for multiplexing - parallel information processing on multiple temporal scales. en_US
dc.description.sponsorship Medical Research Council; The Wolfson Foundation; National Institutes of Health; The Royal Society en_US
dc.language.iso en en_US
dc.publisher Frontiers Research Foundation en_US
dc.rights Copyright 2008 Roopun, Kramer, Carracedo, Kaiser, Davies, Traub, Kopell and Whittington. This is an open-access article subject to an exclusive license agreement between the authors and the Frontiers Research Foundation, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are credited. en_US
dc.rights.uri en_US
dc.subject Neocortex en_US
dc.subject Gamma rhythm en_US
dc.subject Beta rhythm en_US
dc.subject Inhibition en_US
dc.title Period Concatenation Underlies Interactions Between Gamma and Beta Rhythms in Neocortex en_US
dc.type article en_US
dc.identifier.doi 10.3389/neuro.03.001.2008 en_US
dc.identifier.pubmedid 18946516 en_US
dc.identifier.pmcid 2525927 en_US

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