URI: http://hdl.handle.net/2144/2714

The Boston University Center for Biomedical Mass Spectrometry joins three basic sciences research units under one roof. Four members of Boston University School of Medicine faculty, associated with the Center, develop and apply high-end instrumentation and methods; these faculty collaborate extensively with other biomedical researchers at BUSM and elsewhere. In addition to its extensive direct funding from NIH and other sources, the Center provides analytical platforms for interdisciplinary NIH grants for a large number of BUSM researchers.

The primary goal of the Center is to develop and disseminate methods and instrumentation to meet emerging bioanalytical needs; the research is investigator-initiated and is not intended to provide a core laboratory function. Another goal is to educate the next generation of researchers in cutting-edge instrumentation, methods and technologies.

The CBMS is the home of the Mass Spectrometry Resource P41 Center. Visit the CMB website for more information.

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  • CD1c Bypasses Lysosomes to Present a Lipopeptide Antigen with 12 Amino Acids 

    Van Rhijn, Ildiko; Young, David C.; De Jong, Annemieke; Vazquez, Jenny; Cheng, Tan-Yun; Talekar, Rahul; Barral, Duarte C.; León, Luis; Brenner, Michael B.; Katz, Joel T.; Riese, Richard; Ruprecht, Ruth M.; O'Connor, Peter B.; Costello, Catherine E.; Porcelli, Steven A.; Briken, Volker; Moody, D. Branch (The Rockefeller University Press, 2009-05-25)
    The recent discovery of dideoxymycobactin (DDM) as a ligand for CD1a demonstrates how a nonribosomal lipopeptide antigen is presented to T cells. DDM contains an unusual acylation motif and a peptide sequence present only ...
  • Acyl Peptide Hydrolase Degrades Monomeric and Oligomeric Amyloid-Beta Peptide 

    Yamin, Rina; Zhao, Cheng; O'Connor, Peter B.; McKee, Ann C.; Abraham, Carmela R. (BioMed Central, 2009-7-23)
    BACKGROUND The abnormal accumulation of amyloid-beta peptide is believed to cause malfunctioning of neurons in the Alzheimer's disease brain. Amyloid-beta exists in different assembly forms in the aging mammalian brain ...