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dc.contributor.authorMolenaar, Esther A.en_US
dc.contributor.authorMassaro, Joseph M.en_US
dc.contributor.authorJacques, Paul F.en_US
dc.contributor.authorPou, Karla M.en_US
dc.contributor.authorEllison, R. Curtisen_US
dc.contributor.authorHoffmann, Udoen_US
dc.contributor.authorPencina, Karolen_US
dc.contributor.authorShadwick, Steven D.en_US
dc.contributor.authorVasan, Ramachandran S.en_US
dc.contributor.authorO'Donnell, Christopher J.en_US
dc.contributor.authorFox, Caroline S.en_US
dc.date.accessioned2011-12-29T21:03:23Z
dc.date.available2011-12-29T21:03:23Z
dc.date.issued2011-12-29
dc.identifier.citationMolenaar, Esther A., Joseph M. Massaro, Paul F. Jacques, Karla M. Pou, R. Curtis Ellison, Udo Hoffmann, Karol Pencina, Steven D. Shadwick, Ramachandran S. Vasan, Christopher J. O'Donnell, Caroline S. Fox. "Association of Lifestyle Factors With Abdominal Subcutaneous and Visceral Adiposity" Diabetes Care 32(3): 505-510. (2009)en_US
dc.identifier.issn1935-5548en_US
dc.identifier.urihttp://hdl.handle.net/2144/2548
dc.description.abstractOBJECTIVE: The purpose of this study was to assess the relationship between lifestyle factors and abdominal subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT) in a community-based setting. RESEARCH DESIGN AND METHODS: Cross-sectional associations between lifestyle factors (dietary quality, physical activity, smoking, and alcohol consumption) and SAT and VAT volumes were examined in 2,926 Framingham Heart Study participants (48.6% women, aged 50 ± 10 years). RESULTS: Diets consistent with the 2005 Dietary Guidelines Adherence Index and greater physical activity were inversely associated with SAT and VAT (P < 0.0001–0.002). In men, former smoking was associated with higher SAT (2,743 ± 56 cm3) compared with current smokers (2,629 ± 88 cm3) or those who never smoked (2,538 ± 44 cm3; P = 0.02). Both former and current smoking was associated with higher VAT (P = 0.03 [women]; P = 0.005 [men]). Women with high amounts of alcohol intake (>7 drinks/week) had lower SAT (2,869 ± 106 cm3) than those who consumed less alcohol (3,184 ± 44 cm3, P = 0.006); significant differences in VAT were not observed (P = 0.18). In men, high amounts of alcohol intake (>14 drinks/week) were associated with higher VAT (2,272 ± 59 cm3) compared with intake of ≤14 drinks/week (2,139 ± 25 cm3, P = 0.04), whereas SAT did not differ (P = 0.91). An increasing number of healthy lifestyle factors were associated with lower SAT and VAT volumes (all P < 0.003). CONCLUSIONS: Adherence to recommended dietary guidelines and physical activity are associated with lower SAT and VAT volumes. However, both smoking and high alcohol intake are differentially associated with VAT volumes. Further research to uncover the putative mechanisms is warranted.en_US
dc.description.sponsorshipNational Institutes of Health's National Heart, Lung, and Blood Institute's Framingham Heart Study (N01-HC-25195); Netherlands Organization for Scientific Research and the Dutch Heart Foundation; National Heart, Lung, and Blood Institutes (2K24 HL 04334)en_US
dc.language.isoenen_US
dc.publisherAmerican Diabetes Associationen_US
dc.rightsCopyright 2009, American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.en_US
dc.titleAssociation of Lifestyle Factors With Abdominal Subcutaneous and Visceral Adiposityen_US
dc.typearticleen_US
dc.identifier.doi10.2337/dc08-1382en_US
dc.identifier.pubmedid19074991en_US
dc.identifier.pmcid2646037en_US


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