Show simple item record

dc.contributor.authorBeard, Jennifer
dc.contributor.authorFeeley, Frank
dc.contributor.authorRosen, Sydney
dc.date2008-10-01
dc.date.accessioned2010-01-28T20:17:07Z
dc.date.available2010-01-28T20:17:07Z
dc.date.issued2010-01-28T20:17:07Z
dc.identifier.urihttp://sph.bu.edu/cihd/index.php?option=com_content&task=view&id=381&Itemid=617095en_US
dc.identifier.urihttp://hdl.handle.net/2144/1305
dc.description.abstractThe impacts of antiretroviral therapy on quality of life, mental health, labor productivity, and economic wellbeing for people living with HIV/AIDS in developing countries are only beginning to be measured. We conducted a systematic literature review to analyze the effect of antiretroviral therapy (ART) on these non-clinical indicators in developing countries and assess the state of research on these topics. Both qualitative and quantitative studies were included, as were peer-reviewed articles, gray literature, and conference abstracts and presentations. Findings are reported from 12 full-length articles, 7 abstracts, and 1 presentation (representing 16 studies). Compared to HIV-positive patients not yet on treatment, patients on ART reported significant improvements in physical, emotional and mental health and daily function. Work performance improved and absenteeism decreased, with the most dramatic changes occurring in the first three months of treatment and then leveling off. Little research has been done on the impact of ART on household wellbeing, with modest changes in child and family wellbeing within households where adults are receiving ART reported so far. Studies from developing countries have not yet assessed non-clinical outcomes of therapy beyond the first year; therefore, longitudinal outcomes are still unknown. As ART roll out extends throughout high HIV prevalence, low-resource countries and is sustained over years and decades, both positive and adverse non-clinical outcomes need to be empirically measured and qualitatively explored in order to support patient adherence and maximize treatment benefits.en_US
dc.relation.ispartofseriesHDDP No. 11.;Health & Development Paper Series
dc.subjectAntiretroviral therapyen_US
dc.subjectQuality of lifeen_US
dc.subjectLabor productivityen_US
dc.subjectHousehold wellbeingen_US
dc.subjectDeveloping countriesen_US
dc.titleNon-clinical outcomes of antiretroviral therapy for HIV/AIDS in developing countries: a systematic literature reviewen_US
dc.typeWorking Paperen_US


Files in this item

This item appears in the following Collection(s)

Show simple item record